Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31607766 | 1.00 | MEN1 (0.52) | MEN1KMT2AMAPTMAOBNPC1 | |
| SCHEMBL1796838 | 0.81 | RAB9A (0.60) | MEN1KMT2AMAPTMAOBNPC1 | |
| SCHEMBL12266910 | 0.81 | CSF1R (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1672 | 0.79 | PTPN1 (0.56) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL354607 | 0.79 | RAB9A (0.61) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL24799555 | 0.79 | RPS6KB1 (0.52) | MAPTRAB9AKDM4EGAACYP1A2 | |
| SCHEMBL16373542 | 0.79 | MAPK1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18618071 | 0.79 | HSD17B1 (0.61) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL20051379 | 0.79 | MEN1 (0.49) | MEN1KMT2AMAPTMAOBNPC1 | |
| SCHEMBL28658856 | 0.79 | NPC1 (0.72) | MEN1KMT2AMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |