SCHEMBL2714729

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2716994	0.91	EPHX2 (0.44)	EPHX2SCN9ARIPK1
	SCHEMBL2717682	0.89	SCN9A (0.54)	EPHX2SCN9APTGESRIPK1KCNH2
	SCHEMBL2717916	0.89	SCN9A (0.41)	EPHX2SCN9ARIPK1ABL1
	SCHEMBL2716379	0.87	GSK3B (0.46)	EPHX2SCN9ATP53ALDH1A1KCNH2
	SCHEMBL2717677	0.85	PTGES (0.45)	EPHX2SCN9APTGESTRPV1
	SCHEMBL2716954	0.85	EPHX2 (0.45)	EPHX2SCN9APTGESALDH1A1RIPK1
	SCHEMBL2715667	0.83	EPHX2 (0.40)	EPHX2SCN9APTGESTP53ALDH1A1
	SCHEMBL2714606	0.83	EPHX2 (0.39)	EPHX2SCN9APTGESTP53ALDH1A1
	SCHEMBL2715291	0.83	EPHX2 (0.43)	EPHX2SCN9AALDH1A1RIPK1KCNH2
	SCHEMBL2715704	0.83	EPHX2 (0.43)	EPHX2SCN9AALDH1A1RIPK1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.