SCHEMBL2717682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2716994	0.91	EPHX2 (0.44)	SCN9AEPHX2RIPK1
	SCHEMBL2714729	0.89	EPHX2 (0.43)	SCN9AEPHX2PTGESRIPK1KCNH2
	SCHEMBL2717039	0.87	GSK3B (0.59)	SCN9AMAPTGSK3BEPHX2PTGES
	SCHEMBL2715208	0.86	SCN9A (0.53)	SCN9AMAPTGSK3BEPHX2PTGES
	SCHEMBL2715345	0.85	SCN9A (0.52)	SCN9AMAPTGSK3BEPHX2PTGES
	SCHEMBL2717916	0.85	SCN9A (0.41)	SCN9AGSK3BEPHX2RIPK1
	SCHEMBL2715665	0.84	SCN9A (0.51)	SCN9AMAPTGSK3BEPHX2PTGES
	SCHEMBL2715900	0.84	SCN9A (0.51)	SCN9AMAPTGSK3BEPHX2PTGES
	SCHEMBL2713503	0.83	SCN9A (0.52)	SCN9AMAPTGSK3BEPHX2PTGES
	SCHEMBL2718610	0.83	PTGES (0.41)	SCN9AMAPTGSK3BEPHX2PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.