SCHEMBL27147697

SCHEMBL27147697

C[Ge](C)(C)c1cccc2c1oc1cc(-c3cccc4c3oc3ccccc34)ncc12

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 5/20 0.36
PIK3CD O00329 1/20 0.35
PIK3CB P42338 1/20 0.35
GGPS1 O95749 1/20 0.34
ATM Q13315 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
AHR P35869 3/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
DRD4 P21917 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27139824 0.83 IDO1 (0.41) MAPTNPC1MEN1KMT2A
SCHEMBL22048839 0.79 ALOX5 (0.47) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL13834440 0.79 ALOX5 (0.47) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL129688 0.77 GRM4 (0.51) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL21204206 0.76 MAOA (0.46) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL19652310 0.76 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL20515188 0.75 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL31406105 0.75 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL13834375 0.75 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL27148338 0.75 AHR (0.33) AHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912724-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-02-27 US disclosed
US-20220348599-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-11-03 US disclosed
EP-4039691-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912724-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device L1CAM, FOXM1, CHRM1 ALOX5 2617/4885PRKDC 4393/4885PIK3CD 4820/4885
US-20220348599-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, FOXM1, CHRM1 ALOX5 2617/4885PRKDC 4393/4885PIK3CD 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.