SCHEMBL27150591

SCHEMBL27150591

O=CC(=O)C(O)(C=O)C(O)C(O)C(O)CO

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19463177 0.89 AKR1B1 (0.30)
SCHEMBL28273882 0.89 AKR1B1 (0.30)
SCHEMBL27762445 0.82 PDE4A (0.46) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL28458638 0.82 PDE4A (0.46) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL28938029 0.81 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL28168488 0.81 USP2 (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6231892 0.81 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7688029 0.81 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL29022778 0.79 USP2 (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL29022779 0.79 USP2 (0.35) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228507-A1 GREEN SOLVENTS FOR CHEMICAL REACTIONS Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2024-07-11 US disclosed
EP-4326725-A1 GREEN SOLVENTS FOR CHEMICAL REACTIONS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2024-02-28 EP disclosed
CN-117321060-A Green solvent for chemical reaction 洛桑联邦理工学院 2023-12-29 CN disclosed
WO-2022223480-A1 GREEN SOLVENTS FOR CHEMICAL REACTIONS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228507-A1 GREEN SOLVENTS FOR CHEMICAL REACTIONS CYP3A4, CYP2F1, CYP2C9 LMNA 4406/4885L3MBTL1 4729/4885PDE4A 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.