SCHEMBL6231892

SCHEMBL6231892

CC(=O)[C@](O)(C=O)[C@@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28938029 1.00 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7688029 1.00 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7893945 0.89 AKR1B1 (0.30)
SCHEMBL27150591 0.81 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL28168488 0.81 USP2 (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL29022779 0.79 USP2 (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL29022778 0.79 USP2 (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL28458638 0.79 PDE4A (0.46) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL27762445 0.79 PDE4A (0.46) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL27870207 0.78 LMNA (0.43) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024168123-A1 SYNTHESIS OF CORE 2 O-SIALYL LEWIS-X POLYSACCHARIDES BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2024-08-15 WO disclosed
US-20050010044-A1 Polysaccharides and methods and intermediates useful for their preparation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-01-13 US disclosed
WO-2005000907-A1 SULFO-PROTECTED POLYSACCHARIDES AND METHODS AND INTERMEDIATES USEFUL FOR THEIR PREPARATION UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-01-06 WO disclosed