SCHEMBL2715063

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266435	0.92	SCN9A (0.51)	EPHX2NR1H4HTR2CSCN9AMAPT
	SCHEMBL2715103	0.89	KCNB1 (0.60)	HTR2CSCN9AMAPTGSK3BNTRK1
	SCHEMBL2714984	0.89	EPHX2 (0.57)	EPHX2NR1H4HTR2CGSK3BALDH1A1
	SCHEMBL2715265	0.88	SCN9A (0.49)	EPHX2NR1H4HTR2CSCN9AMAPT
	SCHEMBL2713250	0.87	RIPK1 (0.52)	SCN9AMAPTGSK3B
	SCHEMBL2715999	0.87	EPHX2 (0.55)	EPHX2NR1H4HTR2CGSK3BALDH1A1
	SCHEMBL2714991	0.86	MAPT (0.56)	EPHX2NR1H4SCN9AMAPTGSK3B
	SCHEMBL2717028	0.86	MAPT (0.51)	SCN9AMAPTGSK3BPPARGPPARA
	SCHEMBL2715551	0.86	MAPT (0.51)	SCN9AMAPTGSK3BKCNB1SCN3A
	SCHEMBL2715370	0.86	MAPT (0.51)	SCN9AMAPTGSK3BKCNB1SCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.