Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886771 | 0.84 | MEN1 (0.47) | KMT2AMEN1SMN1; SMN2L3MBTL1BACE1 | |
| SCHEMBL29853520 | 0.83 | HPGD (0.52) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL898733 | 0.83 | HPGD (0.52) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL18908923 | 0.80 | GPR3 (0.41) | POLBALDH1A1GAATHRB | |
| SCHEMBL16930305 | 0.79 | HTT (0.44) | KMT2AMEN1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL15524132 | 0.79 | PPARG (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL26810800 | 0.78 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1GAA | |
| SCHEMBL19925456 | 0.77 | SMN1; SMN2 (0.42) | KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5954084 | 0.77 | HPGD (0.42) | KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL30636513 | 0.77 | GPR3 (0.41) | KMT2AMEN1POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |