Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146168 | 0.84 | KMT2A (0.38) | CA9KMT2ALMNAGAA | |
| SCHEMBL27142451 | 0.81 | KCNJ1 (0.42) | CA9KMT2AMEN1ALOX12MAPT | |
| SCHEMBL27136905 | 0.74 | LMNA (0.42) | CA9KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28628118 | 0.73 | KMT2A (0.43) | KMT2AMAPTLMNAGAAPOLB | |
| SCHEMBL31389606 | 0.71 | KMT2A (0.44) | KMT2AALOX12MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3309074 | 0.70 | CYP1A2 (0.40) | KMT2AMEN1ALDH1A1RXFP1GAA | |
| SCHEMBL27152236 | 0.70 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL31389811 | 0.70 | MAPT (0.37) | KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL28923147 | 0.69 | KMT2A (0.42) | CA9KMT2AMAPTALDH1A1GAA | |
| SCHEMBL28923148 | 0.69 | KMT2A (0.42) | CA9KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |