SCHEMBL2716601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714120	0.91	SCN9A (0.38)	SCN9AMAPTGSK3BPTGESKDM4E
	SCHEMBL2716257	0.90	SCN9A (0.47)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2715586	0.89	MAPT (0.56)	SCN9AMAPTGSK3BPTGESKLKB1
	SCHEMBL2715922	0.88	CCR3 (0.38)	SCN9AMAPTGSK3BKDM4EMEN1
	SCHEMBL2715345	0.88	SCN9A (0.52)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2714201	0.85	SCN9A (0.47)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2715901	0.83	SCN9A (0.51)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2715341	0.82	MAPT (0.47)	SCN9AMAPTGSK3BADORA3KDM4E
	SCHEMBL2715537	0.81	CD274 (0.40)	SCN9AMAPTADORA3KDM4EMEN1
	SCHEMBL2714698	0.81	SCN9A (0.48)	SCN9AMAPTGSK3BPTGESADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.