SCHEMBL2715396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266303	0.94	SCN9A (0.47)	SCN9ARIPK1CTSDKCNB1EPHX2
	SCHEMBL2713199	0.93	SCN9A (0.48)	SCN9ARIPK1KCNB1ADORA2AADORA2B
	SCHEMBL2714516	0.91	SCN9A (0.49)	SCN9ARIPK1KCNB1ADORA2AADORA2B
	SCHEMBL2714499	0.90	RIPK1 (0.51)	RIPK1ADORA2AADORA2BADORA1
	SCHEMBL2716384	0.88	SCN9A (0.53)	SCN9AKCNB1SCN3AROCK2PTGES
	SCHEMBL2713034	0.88	RIPK1 (0.44)	SCN9ARIPK1CTSDADORA2AADORA2B
	SCHEMBL2714916	0.87	EPHX2 (0.53)	SCN9AKCNB1EPHX2PPARGPTGES
	SCHEMBL2715551	0.86	MAPT (0.51)	SCN9ARIPK1CTSDKCNB1SCN3A
	SCHEMBL2714077	0.86	SCN9A (0.50)	SCN9AMMP13
	SCHEMBL2717869	0.84	RIPK1 (0.54)	SCN9ARIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.