SCHEMBL2716384

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266802	0.93	SCN9A (0.52)	SCN9AROCK2SCN3ASCN1ASCN5A
	SCHEMBL2714516	0.92	SCN9A (0.49)	SCN9AROCK2KCNB1WDR5
	SCHEMBL2713199	0.90	SCN9A (0.48)	SCN9AROCK2SCN3AKCNB1
	SCHEMBL2714086	0.90	ROCK2 (0.50)	SCN9AROCK2SCN3ASCN1ASCN5A
	SCHEMBL2715396	0.88	SCN9A (0.48)	SCN9AROCK2SCN3AKCNB1PTGES
	SCHEMBL2715174	0.86	SCN9A (0.51)	SCN9AKCNH2KCNB1LMNAWDR5
	SCHEMBL2713838	0.86	SCN9A (0.55)	SCN9AROCK2SCN3ASCN1ASCN5A
	SCHEMBL2714916	0.86	EPHX2 (0.53)	SCN9AKCNB1PTGESGAA
	SCHEMBL2715099	0.84	SCN9A (0.56)	SCN9AROCK2SCN3A
	SCHEMBL2715135	0.83	KCNB1 (0.56)	SCN9AROCK2KCNH2KCNB1WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.