SCHEMBL27156

SCHEMBL27156

C=CCOc1ccc(C(C)(C)c2c(Br)c(Br)c(OCC=C)c(Br)c2Br)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
TP53 P04637 3/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
MAPT P10636 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 5/20 0.36
CHRNB2 P17787 3/20 0.36
CHRNB4 P30926 3/20 0.36
CHRNA3 P32297 3/20 0.36
CHRNA4 P43681 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP2D6 P10635 1/20 0.35
GAA P10253 2/20 0.35
ADRB2 P07550 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818909 0.87 MAPT (0.39) NPC1RAB9ATP53CA12CA1
SCHEMBL824168 0.81 CA12 (0.49) NPC1RAB9ATP53CA12CA1
SCHEMBL4570343 0.81 CA12 (0.49) NPC1RAB9ATP53CA12CA1
SCHEMBL9742852 0.77 ALDH1A1 (0.45) NPC1RAB9ATP53CA12CA1
SCHEMBL15869178 0.77 CA12 (0.45) NPC1RAB9ATP53CA12CA1
SCHEMBL4398260 0.76
SCHEMBL5424245 0.75 SMN1; SMN2 (0.51) TP53MAPTSMN1; SMN2POLBALDH1A1
SCHEMBL11121843 0.75 SMN1; SMN2 (0.57) NPC1RAB9ACA12CA1CA2
SCHEMBL20233954 0.75 MAPT (0.55) NPC1RAB9ATP53CA12CA1
SCHEMBL12370719 0.75 ALDH1A1 (0.51) NPC1RAB9ATP53CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773670-B Methyl octabromoether flame-retardant master batch containing multicomponent compatilizer and flame-retardant polystyrene foam material thereof 北京工商大学 2023-11-14 CN claimed
CN-114773670-A Methyl octabromoether flame-retardant master batch containing multi-component compatilizer and flame-retardant polystyrene foam material thereof 北京工商大学 2022-07-22 CN claimed
CN-114591152-A Synthetic method of phenol-based alkenyl alkyl ether 潍坊裕凯化工有限公司 2022-06-07 CN claimed
CN-114105740-A Preparation method of tetrabromobisphenol A-bis (2, 3-dibromopropyl) ether 宿迁联盛科技股份有限公司 2022-03-01 CN claimed
JP-10195012-A None JP disclosed
CN-114773670-B Methyl octabromoether flame-retardant master batch containing multicomponent compatilizer and flame-retardant polystyrene foam material thereof 北京工商大学 2023-11-14 CN disclosed
CN-114773670-A Methyl octabromoether flame-retardant master batch containing multi-component compatilizer and flame-retardant polystyrene foam material thereof 北京工商大学 2022-07-22 CN disclosed
CN-114591152-A Synthetic method of phenol-based alkenyl alkyl ether 潍坊裕凯化工有限公司 2022-06-07 CN disclosed
CN-114591152-A Synthetic method of phenol-based alkenyl alkyl ether 潍坊裕凯化工有限公司 2022-06-07 CN disclosed
CN-114105740-A Preparation method of tetrabromobisphenol A-bis (2, 3-dibromopropyl) ether 宿迁联盛科技股份有限公司 2022-03-01 CN disclosed
CN-114105740-A Preparation method of tetrabromobisphenol A-bis (2, 3-dibromopropyl) ether 宿迁联盛科技股份有限公司 2022-03-01 CN disclosed
CN-113735692-A Preparation method of tetrabromobisphenol A diene alkyl ether 潍坊裕凯化工有限公司 2021-12-03 CN disclosed
WO-2009080464-A2 PROCESS FOR THE PRODUCTION OF INSECTICIDE-MODIFIED BEAD MATERIAL COMPOSED OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-MODIFIED MOLDINGS OBTAINABLE THEREFROM BASF SE (DE) 2009-07-02 WO disclosed
WO-2009080487-A2 INSECTICIDE-MODIFIED BEAD MATERIAL COMPOSED OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-MODIFIED MOLDINGS OBTAINABLE THEREFROM BASF SE (DE) 2009-07-02 WO disclosed
EP-1812726-A1 IMPACT-ABSORBING MEMBERS FOR DYNAMIC IMPACT APPLICATIONS Dow Gloval Technologies Inc. (US) 2007-08-01 EP disclosed
US-20060148919-A1 Impact-absorbing members for dynamic impact applications DOW GLOBAL TECHNOLOGIES LLC 2006-07-06 US disclosed
WO-2006053029-A1 IMPACT-ABSORBING MEMBERS FOR DYNAMIC IMPACT APPLICATIONS DOW GLOBAL TECHNOLOGIES, INC. (US) 2006-05-18 WO disclosed
JP-H10195012-A PRODUCTION OF HIGH-PURITY, FINE PARTICLES OF TETRABROMOBISPHENOL-A DIALLYL ETHER TOSOH CORP 1998-07-28 JP disclosed
EP-0382312-B1 A curable polyphenylene ether resin composition and a cured resin composition obtainable therefrom ASAHI CHEMICAL IND (JP) 1995-07-12 EP disclosed
US-5218030-A Storage stability; chemical and heat resistance, dimensional stability; electronics ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed