Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27156 | 0.87 | NPC1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL11189152 | 0.82 | NQO1 (0.44) | MAPTNPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL4570343 | 0.80 | CA12 (0.49) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL824168 | 0.80 | CA12 (0.49) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL1825311 | 0.79 | ESR1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL29657179 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2TP53ALDH1A1KDM4EHPGD | |
| SCHEMBL7199396 | 0.79 | HTT (0.46) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3618538 | 0.79 | HPGD (0.39) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10595211 | 0.77 | MAPK1 (0.41) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL9742852 | 0.76 | ALDH1A1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358798-B2 | COMPOSITIONS OF EXPANDABLE VINYL AROMATIC POLYMERS WITH AN IMPROVED THERMAL INSULATION CAPACITY, PROCESS FOR THEIR PRODUCTION AND EXPANDED ARTICLES OBTAINED THEREFROM | VERSALIS SPA (IT) | 2021-08-18 | — | — | EP | disclosed |
| US-10961365-B2 | Compositions of expandable vinyl aromatic polymers with an improved thermal insulation capacity, process for their production and expanded articles obtained therefrom | VERSALIS S.P.A. (IT) | 2021-03-30 | — | — | US | disclosed |
| US-20180273717-A1 | COMPOSITIONS OF EXPANDABLE VINYL AROMATIC POLYMERS WITH AN IMPROVED THERMAL INSULATION CAPACITY, PROCESS FOR THEIR PRODUCTION AND EXPANDED ARTICLES OBTAINED THEREFROM | POLIMERI EUROPA S.P.A. (IT) | 2018-09-27 | — | — | US | disclosed |
| EP-2358798-B1 | COMPOSITIONS OF EXPANDABLE VINYL AROMATIC POLYMERS WITH AN IMPROVED THERMAL INSULATION CAPACITY, PROCESS FOR THEIR PRODUCTION AND EXPANDED ARTICLES OBTAINED THEREFROM | VERSALIS SPA (IT) | 2015-02-11 | — | — | EP | disclosed |
| US-20110284793-A1 | COMPOSITIONS OF EXPANDABLE VINYL AROMATIC POLYMERS WITH AN IMPROVED THERMAL INSULATION CAPACITY, PROCESS FOR THEIR PRODUCTION AND EXPANDED ARTICLES OBTAINED THEREFROM | POLIMERI EUROPA S.P.A. (IT) | 2011-11-24 | — | — | US | disclosed |
| EP-2358798-A1 | COMPOSITIONS OF EXPANDABLE VINYL AROMATIC POLYMERS WITH AN IMPROVED THERMAL INSULATION CAPACITY, PROCESS FOR THEIR PRODUCTION AND EXPANDED ARTICLES OBTAINED THEREFROM | Polimeri Europa S.p.A. (IT) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010069584-A1 | COMPOSITIONS OF EXPANDABLE VINYL AROMATIC POLYMERS WITH AN IMPROVED THERMAL INSULATION CAPACITY, PROCESS FOR THEIR PRODUCTION AND EXPANDED ARTICLES OBTAINED THEREFROM | POLIMERI EUROPA S.P.A. (IT) | 2010-06-24 | — | — | WO | disclosed |