Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931807 | 0.85 | MLYCD (0.62) | MLYCDHDAC1HPGDCYP3A4CYP2D6 | |
| SCHEMBL2718344 | 0.84 | NAMPT (0.51) | NAMPTMLYCDTACR1KDM1AHDAC1 | |
| SCHEMBL27931803 | 0.84 | L3MBTL1 (0.62) | NAMPTMLYCDKDM1AHDAC1EGLN1 | |
| SCHEMBL2715156 | 0.83 | NAMPT (0.49) | NAMPTMLYCDTACR1KDM1AHDAC1 | |
| SCHEMBL28094014 | 0.82 | VNN1 (0.45) | TACR1WDR5ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2715620 | 0.82 | SCN9A (0.56) | NAMPTMLYCDTACR1KDM1AHDAC1 | |
| SCHEMBL27913768 | 0.80 | MMP13 (0.50) | NAMPTMLYCDTACR1ALDH1A1CYP3A4 | |
| SCHEMBL2717667 | 0.80 | GSK3B (0.53) | NAMPT | |
| SCHEMBL6253464 | 0.79 | MLYCD (0.60) | MLYCDTACR1KDM1AHDAC1ALDH1A1 | |
| SCHEMBL27913563 | 0.79 | DDR1 (0.47) | KDM1AHDAC1WDR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249721-A | Arylamine Derivatives as TTX-S Blockers | RAQUALIA PHARMA INC | 2013-08-14 | — | — | CN | claimed |
| CN-103249721-A | Arylamine Derivatives as TTX-S Blockers | RAQUALIA PHARMA INC | 2013-08-14 | — | — | CN | disclosed |