Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27156314 | 0.92 | DAO (0.37) | FNTAFNTBCCR2MAPTCYP1A2 | |
| SCHEMBL27156306 | 0.91 | AKR1C3 (0.43) | FNTAFNTBMAPTPOLBCYP1A2 | |
| SCHEMBL27156303 | 0.88 | NPC1 (0.37) | FNTAFNTBMAPTNPSR1POLB | |
| SCHEMBL27156311 | 0.85 | RAB9A (0.40) | MAPTNPSR1POLBCYP1A2CYP2D6 | |
| SCHEMBL27156310 | 0.85 | TRPA1 (0.37) | FNTAFNTBPOLBMEN1KMT2A | |
| SCHEMBL30816139 | 0.84 | KMT2A (0.39) | FNTAFNTBMAPTNPSR1POLB | |
| SCHEMBL28458417 | 0.77 | MAPT (0.36) | MAPTNPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27181989 | 0.77 | DHODH (0.40) | NR4A1FNTAFNTBMAPTNPSR1 | |
| SCHEMBL30816138 | 0.77 | HPGD (0.41) | MAPTNPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27156301 | 0.76 | MEN1 (0.39) | MAPTPOLBL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11919900-B1 | 1-substituted benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate derivatives as antitubercular agents | King Faisal University (SA) | 2024-03-05 | — | — | US | claimed |
| US-11919900-B1 | 1-substituted benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate derivatives as antitubercular agents | King Faisal University (SA) | 2024-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919900-B1 | 1-substituted benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate derivatives as antitubercular agents | BRD4, BET1, TALDO1 | NR4A1 910/4885FNTA 720/4885FNTB 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.