SCHEMBL2715710

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2717026	0.90	SCN10A (0.45)	SCN10AROCK2ROCK1EPHX2NR1H4
	SCHEMBL2715265	0.89	SCN9A (0.49)	SCN10AROCK2ROCK1EPHX2NR1H4
	SCHEMBL2715787	0.89	GSK3B (0.54)	—
	SCHEMBL2714984	0.88	EPHX2 (0.57)	SCN10ARIPK1EPHX2NR1H4HTR2C
	SCHEMBL2714802	0.87	ROCK2 (0.60)	RIPK1ROCK2ROCK1HTR2CMAPK14
	SCHEMBL2713833	0.85	GSK3B (0.44)	ROCK1SMN1; SMN2GAA
	SCHEMBL2718118	0.85	RIPK1 (0.46)	RIPK1ROCK2ROCK1EPHX2NR1H4
	SCHEMBL18266202	0.85	TACR1 (0.48)	ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
	SCHEMBL18266417	0.83	SMN1; SMN2 (0.43)	SCN10AROCK2ROCK1EPHX2ALDH1A1
	SCHEMBL28806897	0.83	ROCK2 (0.62)	ROCK2ROCK1EPHX2NR1H4HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.