Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176272 | 0.78 | KDM4E (0.37) | OPRM1OPRD1OPRK1KDM4ESLC22A1 | |
| SCHEMBL22220530 | 0.78 | KDM4E (0.37) | OPRM1OPRD1OPRK1KDM4ESLC22A1 | |
| SCHEMBL27660443 | 0.71 | ALDH1A1 (0.38) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL10842293 | 0.69 | OPRM1 (0.40) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL21265902 | 0.65 | SMN1; SMN2 (0.38) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6159601 | 0.65 | ALDH1A1 (0.36) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6159606 | 0.65 | OPRM1 (0.42) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL29947651 | 0.64 | OPRM1 (0.46) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL24894664 | 0.64 | OPRM1 (0.46) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL10638484 | 0.64 | POLB (0.40) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4332105-A1 | PYRIDINO- OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-03-06 | — | — | EP | disclosed |