Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 7/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27204297 | 1.00 | HCRTR2 (0.41) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL29912773 | 0.85 | IDH1 (0.44) | HCRTR2HCRTR1LOXL2 | |
| SCHEMBL27158685 | 0.83 | HCRTR2 (0.40) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL27158681 | 0.83 | HCRTR2 (0.40) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL29913026 | 0.81 | HCRTR2 (0.38) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL27157981 | 0.81 | HCRTR2 (0.38) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL27204216 | 0.81 | HCRTR2 (0.38) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL29912797 | 0.81 | P2RX7 (0.46) | HCRTR2HCRTR1LOXL2MGLLHTR1A | |
| SCHEMBL29912961 | 0.81 | HCRTR2 (0.38) | HCRTR2HCRTR1LOXL2HTR1AP2RX7 | |
| SCHEMBL29912812 | 0.79 | GHSR (0.44) | LOXL2MGLLHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |