SCHEMBL271587

SCHEMBL271587

C=Cc1ccc(N=Nc2ccc(C=C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.65
▸ TSHR P16473 2/20 0.48
▸ MEN1 O00255 4/20 0.41
▸ KMT2A Q03164 4/20 0.41
▸ TDP1 Q9NUW8 4/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ HDAC8 Q9BY41 2/20 0.40
▸ PKM P14618 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ CYP2C19 P33261 1/20 0.33
▸ GLB1 P16278 1/20 0.33
▸ CTRB1 P17538 1/20 0.33
▸ CTRC Q99895 1/20 0.33
▸ TP53 P04637 1/20 0.32
▸ CHRNB2 P17787 1/20 0.31
▸ CHRNB4 P30926 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271586 1.00 ALDH1A1 (0.65) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL3312607 0.90 ALDH1A1 (0.59) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL28525044 0.90 ALDH1A1 (0.59) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL27933386 0.84 ALDH1A1 (0.52) ALDH1A1TSHRMEN1KMT2ATDP1
Azobenzene SCHEMBL27886536 0.81 ALDH1A1 (0.70) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL7639 0.80 ALDH1A1 (1.00) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL473081 0.80 ALDH1A1 (1.00) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL15748432 0.80 ALDH1A1 (0.61) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL19851313 0.79 ALDH1A1 (0.46) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL13823021 0.78 ALDH1A1 (0.58) ALDH1A1TSHRMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024246941-A1 A COMBINATION OF SUCCINATE CONSUMING MICROBIOTAS TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) 2024-12-05 — — WO claimed
US-11980877-B1 4,4′-divinylazobenzene-bridged diruthenium complex bearing Ru(CO)Cl(PiPr3)2 moieties as an inorganic catalyst King Faisal University (SA) 2024-05-14 — — US claimed
US-11981691-B1 1,4-divinylphenylene-bridged diruthenium complex bearing two Ru(CO)(2-mercaptoquinolato)(PIPR3)2 moieties as an organic catalyst King Faisal University (SA) 2024-05-14 — — US claimed
US-11945828-B1 Electronically weakly coupled 4,4′-divinylazobenzene-bridged diruthenium complex bearing two Ru(CO)Cl (PiPr3)2 moieties as an inorganic catalyst King Faisal University (SA) 2024-04-02 — — US claimed
US-9890351-B2 Encapsulates THE PROCTER & GAMBLE COMPANY (US) 2018-02-13 — — US claimed
EP-2741731-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2017-05-17 — — EP claimed
EP-2741731-A1 ENCAPSULATES The Procter and Gamble Company (US) 2014-06-18 — — EP claimed
US-20130039962-A1 ENCAPSULATES ENCAPSYS, LLC 2013-02-14 — — US claimed
WO-2013022949-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2013-02-14 — — WO claimed
US-4663308-A Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract MEDICAL COLLEGE OF OHIO (US) 1987-05-05 — — US claimed
WO-2024246941-A1 A COMBINATION OF SUCCINATE CONSUMING MICROBIOTAS TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) 2024-12-05 — — WO disclosed
US-11987596-B1 Polyelectrochromism of electronically weakly coupled 4,4′-divinylazoarylene-bridged two Ru(CO)Cl(PiPr3)2 entities King Faisal University (SA) 2024-05-21 — — US disclosed
US-11986809-B1 4,4-divinylazoarylene-bridged diruthenium complex bearing Ru(CO)Cl(PiPr3)2 as an inorganic catalyst King Faisal University (SA) 2024-05-21 — — US disclosed
US-11980877-B1 4,4′-divinylazobenzene-bridged diruthenium complex bearing Ru(CO)Cl(PiPr3)2 moieties as an inorganic catalyst King Faisal University (SA) 2024-05-14 — — US disclosed
US-11980877-B1 4,4′-divinylazobenzene-bridged diruthenium complex bearing Ru(CO)Cl(PiPr3)2 moieties as an inorganic catalyst King Faisal University (SA) 2024-05-14 — — US disclosed
US-5407682-A Process for the preparation of azo-and /or disulfide polymer matrix drug delivery system for the site specific delivery of an active agent in the colon DANBIOSYST UK LTD AISHA (GB) 1995-04-18 — — US disclosed
EP-0513035-B1 PROCESS FOR THE PREPARATION OF AZO- AND/OR DISULFIDE-CONTAINING POLYMERS DANBIOSYST UK (GB) 1993-10-20 — — EP disclosed
US-5032572-A Drug delivery MEDICAL COLLEGE OF OHIO (US) 1991-07-16 — — US disclosed
US-4826954-A Diorganopolysiloxane-azobenzene alternating copolymers and methods for their preparation TORAY SILICONE CO., LTD. (JP) 1989-05-02 — — US disclosed
US-4663308-A Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract MEDICAL COLLEGE OF OHIO (US) 1987-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130039962-A1 ENCAPSULATES ABCB4, PPIB, FLNB ALDH1A1 696/4885TSHR 4882/4885MEN1 1592/4885
US-11986809-B1 4,4-divinylazoarylene-bridged diruthenium complex bearing Ru(CO)Cl(PiPr3)2 as an inorganic catalyst PIP4K2A, PIP4K2B, PIP4K2C ALDH1A1 2844/4885TSHR 3696/4885MEN1 4093/4885
US-11980877-B1 4,4′-divinylazobenzene-bridged diruthenium complex bearing Ru(CO)Cl(PiPr3)2 moieties as an inorganic catalyst PIP4K2B, PIP4K2C, PI4K2B ALDH1A1 3753/4885TSHR 3793/4885MEN1 4077/4885
US-11945828-B1 Electronically weakly coupled 4,4′-divinylazobenzene-bridged diruthenium complex bearing two Ru(CO)Cl (PiPr3)2 moieties as an inorganic catalyst PIP4K2B, PIP4K2C, PIP4K2A ALDH1A1 3755/4885TSHR 3840/4885MEN1 4091/4885
US-11981691-B1 1,4-divinylphenylene-bridged diruthenium complex bearing two Ru(CO)(2-mercaptoquinolato)(PIPR3)2 moieties as an organic catalyst PIP4K2A, PIP4K2B, PIP5K1A ALDH1A1 2526/4885TSHR 4092/4885MEN1 3452/4885
US-11987596-B1 Polyelectrochromism of electronically weakly coupled 4,4′-divinylazoarylene-bridged two Ru(CO)Cl(PiPr3)2 entities BICRA, LIG3, PIP4K2A ALDH1A1 4143/4885TSHR 3192/4885MEN1 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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