SCHEMBL2715901

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714686	0.92	ROCK2 (0.43)	SCN9AROCK2ROCK1EPHX2NR1H4
	SCHEMBL2714201	0.91	SCN9A (0.47)	SCN9AROCK2ROCK1MAPTGSK3B
	SCHEMBL2715885	0.87	MAPT (0.56)	SCN9AROCK2ROCK1MAPTGSK3B
	SCHEMBL2715269	0.85	SCN9A (0.47)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2716601	0.83	SCN9A (0.47)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2715174	0.83	SCN9A (0.51)	SCN9AMAPTGSK3BPTGESCCR3
	SCHEMBL2716814	0.82	EPHX2 (0.42)	SCN9AEPHX2ADORA3CHRNB2CHRNB4
	SCHEMBL2715226	0.81	SCN9A (0.47)	SCN9AMAPTGSK3BADORA3CCR3
	SCHEMBL2717417	0.81	SCN9A (0.61)	SCN9AMAPTGSK3BPTGESCCR3
	SCHEMBL2716257	0.81	SCN9A (0.47)	SCN9AMAPTGSK3BPTGESADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.