SCHEMBL2716031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715735	0.87	GSK3B (0.42)	SCN9ARIPK1PIK3CAGPBAR1TACR1
	SCHEMBL2717016	0.85	GRM5 (0.41)	GRM5SCN9AHCRTR1HCRTR2TACR1
	SCHEMBL2712842	0.83	SCN9A (0.45)	SCN9ARIPK1PIK3CA
	SCHEMBL2717407	0.82	SCN9A (0.41)	SCN9ARIPK1PIK3CAHCRTR1HCRTR2
	SCHEMBL2714027	0.78	GSK3B (0.41)	SCN9AGPBAR1TACR1
	SCHEMBL2715030	0.78	RIPK1 (0.38)	GRM5SCN9ARIPK1PIK3CAHCRTR1
	SCHEMBL2716166	0.76	SCN9A (0.46)	SCN9ARIPK1PIK3CA
	SCHEMBL2715839	0.76	SCN9A (0.39)	SCN9ARIPK1PIK3CAHCRTR1HCRTR2
	SCHEMBL2716160	0.75	GSK3B (0.42)	GRM5MEN1KMT2ACCR3
	SCHEMBL2715479	0.75	SCN9A (0.45)	SCN9ARIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.