SCHEMBL2717016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2716160	0.89	GSK3B (0.42)	GRM5L3MBTL1CACNA1GCACNA1HCACNA1I
	SCHEMBL2716031	0.85	GRM5 (0.37)	GRM5PHGDHSCN9AHCRTR1HCRTR2
	SCHEMBL2714968	0.83	EPHX2 (0.46)	L3MBTL1CACNA1GCACNA1HCACNA1ITRPV1
	SCHEMBL2715030	0.83	RIPK1 (0.38)	GRM5SCN9AHCRTR1HCRTR2EPHX2
	SCHEMBL2715915	0.77	EPHX2 (0.41)	SCN9AEPHX2
	SCHEMBL18266620	0.77	EPHX2 (0.41)	SCN9AEPHX2
	SCHEMBL2716820	0.76	EPHX2 (0.40)	SCN9AEPHX2
	SCHEMBL2718584	0.76	EPHX2 (0.41)	L3MBTL1TRPV1SCN9AEPHX2
	SCHEMBL2713853	0.76	EPHX2 (0.56)	SCN9AEPHX2
	SCHEMBL2715935	0.75	SCN9A (0.40)	SCN9AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.