Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 8/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27164223 | 1.00 | IL4I1 (0.61) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL27164229 | 1.00 | IL4I1 (0.61) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL30046025 | 0.99 | IL4I1 (0.60) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL27163079 | 0.85 | IL4I1 (0.74) | IL4I1RXFP1POLBHRH3TP53 | |
| SCHEMBL27163306 | 0.85 | IL4I1 (0.77) | IL4I1RXFP1POLBHRH3TP53 | |
| SCHEMBL30948225 | 0.85 | IL4I1 (0.62) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL30947971 | 0.84 | IL4I1 (0.61) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL30948340 | 0.83 | IL4I1 (0.60) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL30947926 | 0.83 | IL4I1 (0.63) | IL4I1RXFP1POLBHRH3BRD4 | |
| SCHEMBL30947901 | 0.81 | IL4I1 (0.57) | IL4I1RXFP1POLBHRH3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
| EP-4329889-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2024-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | IL4I1 1/4885RXFP1 1354/4885POLB 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.