SCHEMBL2716486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714015	0.89	ALDH1A1 (0.43)	MAPK1ALDH1A1LMNAKMT2AHTT
	SCHEMBL27931880	0.87	MAPK1 (0.42)	MAPK1ALDH1A1LMNAKMT2AHTT
	SCHEMBL2716201	0.86	L3MBTL1 (0.43)	MAPK1SMN1; SMN2SCN9ASSTR4AAK1
	SCHEMBL15350899	0.85	SCN9A (0.47)	MAPK1KMT2AHTTSMN1; SMN2SCN9A
	SCHEMBL15351020	0.85	SSTR4 (0.41)	SCN9ASSTR4AAK1MAPT
	SCHEMBL2714723	0.83	SCN9A (0.37)	MAPK1ALDH1A1LMNAKMT2AHTT
	SCHEMBL2714880	0.80	SCN9A (0.39)	LMNASCN9AAAK1NPSR1MAPT
	SCHEMBL17247992	0.80	MAPK1 (0.43)	MAPK1ALDH1A1LMNASCN9ASSTR4
	SCHEMBL15350870	0.78	MAPK1 (0.41)	MAPK1ALDH1A1LMNAKMT2AHTT
	SCHEMBL15350975	0.78	SCN9A (0.40)	SCN9ASSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.