Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079472 | 1.00 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL31079609 | 1.00 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27165646 | 1.00 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27165370 | 1.00 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27165389 | 0.83 | HTR2A (0.46) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27204460 | 0.83 | HTR2A (0.46) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27204372 | 0.83 | HTR2A (0.49) | HTR2AHTR2CCHRM2CHRM1CHRNB4 | |
| SCHEMBL27165366 | 0.83 | HTR2A (0.49) | HTR2AHTR2CCHRM2CHRM1CHRNB4 | |
| SCHEMBL30816422 | 0.79 | KDM4E (0.46) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL7252886 | 0.77 | HTR7 (0.42) | CHRNB4CHRNA3HRH1HRH3CHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581018-A1 | INDAZOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Mindset Pharma Inc. (CA) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024044848-A1 | INDAZOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-03-07 | — | — | WO | disclosed |