Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27204460 | 1.00 | HTR2A (0.46) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL30816422 | 0.87 | KDM4E (0.46) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27204380 | 0.84 | HTR2A (0.43) | HTR2AHTR2CCHRM2CHRM1 | |
| SCHEMBL27165383 | 0.84 | HTR2A (0.43) | HTR2AHTR2CCHRM2CHRM1 | |
| SCHEMBL31079472 | 0.83 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27165646 | 0.83 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL31079609 | 0.83 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27165384 | 0.83 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL27165370 | 0.83 | HTR2A (0.51) | HTR2AHTR2CHTR2BCHRM2CHRM1 | |
| SCHEMBL30816404 | 0.73 | PDE8B (0.44) | HTR2AHTR2CHTR2BCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044848-A1 | INDAZOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-03-07 | — | — | WO | disclosed |