Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700389 | 0.83 | DRD2 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL3703112 | 0.83 | DRD2 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL3700392 | 0.83 | DRD2 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL2730166 | 0.76 | GPR119 (0.45) | — | |
| SCHEMBL2728781 | 0.69 | GPR119 (0.42) | — | |
| SCHEMBL2732558 | 0.67 | GPR119 (0.54) | — | |
| SCHEMBL23461712 | 0.66 | KDM4E (0.49) | KDM4EHCRTR2ALDH1A1HPGD | |
| SCHEMBL2729792 | 0.63 | DRD2 (0.38) | KDM4EHCRTR2ALDH1A1 | |
| SCHEMBL3699548 | 0.63 | GPR119 (0.41) | — | |
| SCHEMBL2730168 | 0.63 | GPR119 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |