Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498538 | 0.93 | FTO (0.55) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL28166971 | 0.82 | FTO (0.62) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL27576029 | 0.82 | FTO (0.62) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL28222145 | 0.82 | FTO (0.62) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL31580193 | 0.81 | FTO (0.55) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL19126622 | 0.81 | FTO (0.49) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29383733 | 0.81 | FTO (0.55) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL334086 | 0.81 | FTO (0.55) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL20833 | 0.79 | FTO (0.67) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29353864 | 0.79 | FTO (0.67) | FTOMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577639-B2 | Rapid bed-side measurement of neutrophil elastase activity in biological fluids | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-03-03 | — | — | US | disclosed |
| US-9809843-B1 | High throughput measurement of DNA base lesion repair capacity | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2017-11-07 | — | — | US | disclosed |
| US-8551764-B2 | Devices for the detection of the presence and/or activity of proteases in biological samples | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2231867-B1 | NOVEL DEVICES FOR THE DETECTION OF THE PRESENCE AND/OR ACTIVITY OF PROTEASES IN BIOLOGICAL SAMPLES | UNIV FLORIDA (US) | 2012-08-08 | — | — | EP | disclosed |
| US-20120135443-A1 | Rapid Bed-Side Measurement of Neutrophil Elastase Activity in Biological Fluids | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2012-05-31 | — | — | US | disclosed |
| US-20120122133-A1 | NOVEL DEVICES FOR THE DETECTION OF THE PRESENCE AND/OR ACTIVITY OF PROTEASES IN BIOLOGICAL SAMPLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2012-05-17 | — | — | US | disclosed |
| EP-2446049-A2 | RAPID BED-SIDE MEASUREMENT OF NEUTROPHIL ELASTASE ACTIVITY IN BIOLOGICAL FLUIDS | University of Florida Research Foundation, Incorporated (US) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010151878-A2 | RAPID BED-SIDE MEASUREMENT OF NEUTROPHIL ELASTASE ACTIVITY IN BIOLOGICAL FLUIDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-12-29 | — | — | WO | disclosed |
| EP-2231867-A2 | NOVEL DEVICES FOR THE DETECTION OF THE PRESENCE AND/OR ACTIVITY OF PROTEASES IN BIOLOGICAL SAMPLES | University of Florida Research Foundation, Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20090258382-A1 | Novel devices for the detection of the presence and/or activity of proteases in biological samples | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2009-10-15 | — | — | US | disclosed |
| WO-2009082445-A2 | NOVEL DEVICES FOR THE DETECTION OF THE PRESENCE AND/OR ACTIVITY OF PROTEASES IN BIOLOGICAL SAMPLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-07-02 | — | — | WO | disclosed |