Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057114 | 1.00 | GRM5 (0.35) | GRM5NAMPTAKR1C3HTR1F | |
| SCHEMBL27166119 | 0.83 | NAMPT (0.34) | GRM5NAMPTAKR1C3HTR1F | |
| SCHEMBL30056225 | 0.83 | NAMPT (0.34) | GRM5NAMPTAKR1C3HTR1F | |
| SCHEMBL27166123 | 0.83 | PKM (0.40) | GRM5NAMPTAKR1C3 | |
| SCHEMBL27166154 | 0.83 | NOTUM (0.33) | GRM5AKR1C3HTR1F | |
| SCHEMBL30055057 | 0.83 | NOTUM (0.33) | GRM5AKR1C3HTR1F | |
| SCHEMBL30057055 | 0.83 | PKM (0.40) | GRM5NAMPTAKR1C3 | |
| SCHEMBL27166028 | 0.79 | NAMPT (0.48) | GRM5NAMPTAKR1C3 | |
| SCHEMBL30056589 | 0.79 | FAAH (0.37) | AKR1C3HTR1F | |
| SCHEMBL27166059 | 0.79 | FAAH (0.37) | AKR1C3HTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334289-A1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | Organon R&D Finland Ltd (FI) | 2024-03-13 | — | — | EP | disclosed |