Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718799 | 0.88 | GPR119 (0.62) | GPR119F2RL3 | |
| SCHEMBL2718798 | 0.88 | GPR119 (0.62) | GPR119F2RL3 | |
| SCHEMBL3697644 | 0.88 | GPR119 (0.62) | GPR119F2RL3 | |
| SCHEMBL2716584 | 0.88 | GPR119 (0.46) | GPR119F2RL3LMNAMEN1KMT2A | |
| SCHEMBL2716582 | 0.88 | GPR119 (0.46) | GPR119F2RL3LMNAMEN1KMT2A | |
| SCHEMBL15234116 | 0.86 | GPR119 (0.42) | GPR119F2RL3LMNAMEN1KMT2A | |
| SCHEMBL15234113 | 0.86 | GPR119 (0.42) | GPR119F2RL3LMNAMEN1KMT2A | |
| SCHEMBL15234114 | 0.86 | GPR119 (0.42) | GPR119F2RL3LMNAMEN1KMT2A | |
| SCHEMBL2717164 | 0.86 | GPR119 (0.44) | GPR119F2RL3LMNAPPARGPPARA | |
| SCHEMBL2732464 | 0.78 | LTB4R (0.41) | LMNAMEN1KMT2APOLBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | claimed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | claimed |
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |