SCHEMBL27167478

SCHEMBL27167478

CCOC(=O)c1cnn(-c2ccc3c(c2)c(C#N)nn3C2CC2)c1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.41
JAK2 O60674 1/20 0.40
JAK1 P23458 1/20 0.40
XDH P47989 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29992520 1.00 SCN9A (0.41) SCN9AJAK2JAK1XDH
SCHEMBL27167502 0.86
SCHEMBL29898225 0.86
SCHEMBL1646923 0.84 SCN9A (0.43) SCN9A
SCHEMBL26619562 0.83 SCN9A (0.42) SCN9AXDH
SCHEMBL29898261 0.82 PFKFB2 (0.41) SCN9AXDH
SCHEMBL27167474 0.82 PFKFB2 (0.41) SCN9AXDH
SCHEMBL1647146 0.81 XDH (0.42) SCN9AXDH
SCHEMBL1647841 0.81 XDH (0.44) XDH
SCHEMBL1647669 0.78 SCN9A (0.40) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160299-B Xanthine oxidase inhibitor 江苏新元素医药科技有限公司 2024-08-16 CN disclosed
US-20240262808-A1 XANTHINE OXIDASE INHIBITOR JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) 2024-08-08 US disclosed
EP-4335844-A1 CLASS OF XANTHINE OXIDASE INHIBITORS Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. (CN) 2024-03-13 EP disclosed
CN-115160299-A Xanthine oxidase inhibitor 江苏新元素医药科技有限公司 2022-10-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262808-A1 XANTHINE OXIDASE INHIBITOR XDH, PNPO, MPO SCN9A 896/4885JAK2 1097/4885JAK1 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.