Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.56 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.50 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 6/20 | 0.44 |
| ▸ | JAK3 | P52333 | 6/20 | 0.44 |
| ▸ | JAK1 | P23458 | 5/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27169611 | 0.94 | LRRK2 (0.59) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL27169592 | 0.92 | LRRK2 (0.61) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL27169600 | 0.90 | LRRK2 (0.56) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL27169579 | 0.86 | LRRK2 (0.64) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL29754170 | 0.84 | TBK1 (0.43) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL22545995 | 0.84 | TBK1 (0.43) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL27169601 | 0.84 | LRRK2 (0.59) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL27169585 | 0.84 | LRRK2 (0.50) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL29754192 | 0.81 | MAP3K7 (0.46) | LRRK2IKBKETBK1MYLK4STK17A | |
| SCHEMBL22544475 | 0.81 | MAP3K7 (0.46) | LRRK2IKBKETBK1MYLK4STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083882-A1 | BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-03-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083882-A1 | BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | JAK3, JAK1, JAK2 | LRRK2 1356/4885IKBKE 320/4885TBK1 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.