Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695662 | 0.87 | GPR119 (0.52) | GPR119CYP2C9TLR9TLR8TLR7 | |
| SCHEMBL2730215 | 0.87 | GPR119 (0.52) | GPR119CYP2C9TLR9TLR8TLR7 | |
| SCHEMBL2730218 | 0.87 | GPR119 (0.52) | GPR119CYP2C9TLR9TLR8TLR7 | |
| SCHEMBL2717649 | 0.85 | GPR119 (0.45) | GPR119CYP2C9 | |
| SCHEMBL2720216 | 0.79 | GPR119 (0.41) | GPR119CYP2C9TLR9TLR8TLR7 | |
| SCHEMBL3698016 | 0.76 | MAOA (0.46) | GPR119 | |
| SCHEMBL3698623 | 0.76 | MAOA (0.46) | GPR119 | |
| SCHEMBL3698015 | 0.76 | MAOA (0.46) | GPR119 | |
| SCHEMBL2730402 | 0.76 | GPR119 (0.52) | GPR119CYP2C9TLR9TLR8TLR7 | |
| SCHEMBL2730399 | 0.76 | GPR119 (0.52) | GPR119CYP2C9TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |