Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000081 | 1.00 | PIK3CA (0.56) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28943227 | 0.96 | PIK3CA (0.53) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23304407 | 0.90 | ALDH1A1 (0.46) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27172385 | 0.87 | PIK3CA (0.53) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30060484 | 0.87 | PIK3CA (0.53) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23684180 | 0.85 | PIK3CA (0.46) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23304305 | 0.82 | CHRM3 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL27681005 | 0.82 | ALDH1A1 (0.63) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23304360 | 0.80 | GAA (0.40) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5247155 | 0.79 | ALDH1A1 (0.54) | PIK3CAALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4339193-A1 | COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | Innovstone Therapeutics Limited (CN) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022237858-A1 | COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-11-17 | — | — | WO | disclosed |
| CN-115340528-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2022-11-15 | — | — | CN | disclosed |