Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000081 | 0.96 | PIK3CA (0.56) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27172434 | 0.96 | PIK3CA (0.56) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23304407 | 0.91 | ALDH1A1 (0.46) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23684180 | 0.86 | PIK3CA (0.46) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23304305 | 0.83 | CHRM3 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL27172385 | 0.83 | PIK3CA (0.53) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30060484 | 0.83 | PIK3CA (0.53) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27681005 | 0.83 | ALDH1A1 (0.63) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5247155 | 0.83 | ALDH1A1 (0.54) | PIK3CAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23304360 | 0.81 | GAA (0.40) | PIK3CAALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |