Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27172355 | 0.84 | HSD11B1 (0.37) | HSD11B1CYP2C9NR1H2CTSKCA1 | |
| SCHEMBL25694410 | 0.81 | CTSK (0.42) | HSD11B1CYP2C9NR1H2CTSKCA1 | |
| SCHEMBL20069820 | 0.81 | CTSK (0.42) | HSD11B1CYP2C9NR1H2CTSKCA1 | |
| SCHEMBL14657161 | 0.81 | BTK (0.49) | HSD11B1CYP2C9CTSKBTKNFKB1 | |
| SCHEMBL24091122 | 0.80 | CTSK (0.41) | HSD11B1CYP2C9NR1H2CTSKCA1 | |
| SCHEMBL30060502 | 0.78 | EPHX2 (0.33) | HSD11B1 | |
| SCHEMBL20413606 | 0.78 | CTSK (0.40) | HSD11B1CYP2C9NR1H2CTSKCA1 | |
| SCHEMBL20147716 | 0.78 | CTSK (0.40) | HSD11B1CYP2C9CTSKCA1CA2 | |
| SCHEMBL31644391 | 0.78 | CTSK (0.40) | HSD11B1CYP2C9NR1H2CTSKCA1 | |
| SCHEMBL20069821 | 0.78 | CTSK (0.40) | HSD11B1CYP2C9NR1H2CTSKCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4339193-A1 | COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | Innovstone Therapeutics Limited (CN) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022237858-A1 | COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-11-17 | — | — | WO | disclosed |