Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613996 | 0.96 | CA12 (0.43) | CA12CA1CA9L3MBTL1KDM4E | |
| SCHEMBL30828333 | 0.85 | CA12 (0.46) | CA12CA1CA9L3MBTL1KDM4E | |
| SCHEMBL21219198 | 0.85 | ALDH1A1 (0.41) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4420431 | 0.85 | L3MBTL1 (0.42) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28541140 | 0.84 | ALDH1A1 (0.43) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28560305 | 0.83 | KMT2A (0.46) | CA12CA1CA9MEN1KMT2A | |
| SCHEMBL21815478 | 0.83 | MEN1 (0.47) | CA1CA9L3MBTL1MEN1KMT2A | |
| SCHEMBL28380826 | 0.82 | TSHR (0.39) | CA1CA9L3MBTL1KDM4EMEN1 | |
| SCHEMBL27208962 | 0.82 | MAPT (0.40) | CA1CA9L3MBTL1KDM4EMEN1 | |
| SCHEMBL28354485 | 0.82 | TSHR (0.39) | CA1CA9L3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337259-A1 | COMPOUNDS FOR DEGRADING ALPHA-SYNUCLEIN AGGREGATES AND USES THEREOF | Aprinoia Therapeutics Limited (HK) | 2024-03-20 | — | — | EP | disclosed |