Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731573 | 1.00 | SYK (0.44) | SYKCNR2 | |
| SCHEMBL10272215 | 0.92 | SYK (0.45) | SYK | |
| SCHEMBL2716675 | 0.91 | SYK (0.51) | SYK | |
| SCHEMBL2716671 | 0.91 | SYK (0.51) | SYK | |
| SCHEMBL2729441 | 0.90 | SYK (0.44) | SYK | |
| SCHEMBL2729448 | 0.90 | SYK (0.44) | SYK | |
| SCHEMBL2718425 | 0.87 | SYK (0.44) | SYK | |
| SCHEMBL2718419 | 0.87 | SYK (0.44) | SYK | |
| SCHEMBL2715926 | 0.86 | SYK (0.42) | SYK | |
| SCHEMBL2715928 | 0.86 | SYK (0.42) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061415-A1 | OXYPYRIMIDINES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061415-A1 | OXYPYRIMIDINES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |