SCHEMBL271815

SCHEMBL271815

CC1=Cc2c(C(C)C)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(C(C)C)cccc21)[SiH](C)C

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.30
FAAH O00519 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
GABRA1 P14867 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30
PTGS1 P23219 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
HTR2B P41595 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5352184 0.88
SCHEMBL2513976 0.86 FAAH (0.30) LMNAFAAHCA1CA2CYP1A2
SCHEMBL389317 0.85
SCHEMBL4078182 0.84
SCHEMBL5346908 0.84 FAAH (0.31) LMNAFAAHCA1CA2CYP1A2
SCHEMBL7640638 0.84 FAAH (0.31) LMNAFAAHCA1CA2CYP1A2
SCHEMBL5610321 0.83
SCHEMBL1041400 0.83
SCHEMBL5609257 0.82
SCHEMBL7928156 0.82 LMNA (0.32) LMNAFAAHCA1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618912-B2 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-20060166813-A1 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2006-07-27 US claimed
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
EP-1058694-B1 Catalyst system, method for its production and its use for the polymerisation of olefins BASELL POLYOLEFINE GMBH (DE) 2003-04-09 EP claimed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US claimed
US-6391989-B1 COORDINATION CATALYST ON SUPPORT; POLYMERIZATION OF ALPHA-OLEFINS BASELL POLYPROPYLEN GMBH (DE) 2002-05-21 US claimed
US-5329033-A Metallocene catalyst, indene containing ligands, alumoxane cocatalyst HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US claimed
US-5278264-A Catalytic polymerizing in presence of a transition metal metallocene HOECHST AG (DE) 1994-01-11 US claimed
EP-2576642-B1 PROCESS FOR PREPARING A SUPPORTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, THE CATALYST SYSTEM AND ITS USE BASELL POLYOLEFINE GMBH (DE) 2017-08-16 EP disclosed
EP-2513166-B1 PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2017-04-05 EP disclosed
EP-1824888-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2017-01-18 EP disclosed
EP-1648946-B1 OLEFIN POLYMERIZATION PROCESS BASELL POLYOLEFINE GMBH (DE) 2015-07-15 EP disclosed
US-8999875-B2 Process for preparing a supported catalyst system for olefin polymerization, the catalyst system and its use BASELL POLYOLEFINE GMBH (DE) 2015-04-07 US disclosed
EP-1740626-B1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE BASELL POLYOLEFINE GMBH (DE) 2014-10-22 EP disclosed
US-5556997-A Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION (US) 1996-09-17 US disclosed
US-5504172-A COORDINATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-04-02 US disclosed
EP-0653433-A1 Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-05-17 EP disclosed
EP-0629631-A2 Novel transition metal compound, and polymerization catalyst containing it MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-21 EP disclosed
US-5329033-A Metallocene catalyst, indene containing ligands, alumoxane cocatalyst HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed
US-5278264-A Catalytic polymerizing in presence of a transition metal metallocene HOECHST AG (DE) 1994-01-11 US disclosed