Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26242971 | 0.82 | PYCR1 (0.39) | PKMMAPTNPC1ALDH1A1HDAC4 | |
| SCHEMBL27181806 | 0.81 | PKM (0.57) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL6329668 | 0.79 | PKM (0.55) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL27180797 | 0.77 | RXFP1 (0.55) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL6329666 | 0.74 | PKM (0.55) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL13545247 | 0.74 | KDM4E (0.56) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL11983425 | 0.73 | KDM4E (0.60) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL18685530 | 0.71 | KDM4E (0.56) | PKMRXFP1KDM4EMAPTNPC1 | |
| SCHEMBL14057000 | 0.71 | PKM (0.46) | PKMRXFP1KDM4ECCR5ALDH1A1 | |
| SCHEMBL4109831 | 0.70 | KDM4E (0.60) | PKMRXFP1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522592-B2 | ERAP inhibitors | UNIVERSITE DE LILLE (FR) | 2026-01-13 | — | — | US | disclosed |
| EP-4263533-B1 | ERAP INHIBITORS | UNIV LILLE (FR) | 2025-08-20 | — | — | EP | disclosed |
| US-20240101542-A1 | ERAP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101542-A1 | ERAP INHIBITORS | ERAP2, ERAP1, ERMP1 | PKM 3547/4885RXFP1 4425/4885KDM4E 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.