SCHEMBL2718299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715156	0.94	NAMPT (0.49)	MLYCDHPGDALDH1A1KDM4ECYP1A2
	SCHEMBL2714261	0.90	MLYCD (0.56)	MLYCDALDH1A1CYP1A2CYP2D6CYP2C19
	SCHEMBL2714653	0.89	MLYCD (0.54)	MLYCDHPGDALDH1A1KDM4ECYP1A2
	SCHEMBL2715403	0.86	SCN9A (0.59)	MLYCDHPGDALDH1A1KDM4ECYP1A2
	SCHEMBL2718889	0.83	RIPK1 (0.44)	KDM1AHDAC1NPSR1SCN9ALMNA
	SCHEMBL2715796	0.83	HDAC1 (0.42)	ALDH1A1KDM1AHDAC1ROS1LMNA
	SCHEMBL2713652	0.83	NR3C2 (0.53)	KDM1AHDAC1ROS1LMNAHTT
	SCHEMBL18266202	0.83	TACR1 (0.48)	MLYCDHPGDALDH1A1KDM4ECYP1A2
	SCHEMBL2718344	0.83	NAMPT (0.51)	MLYCDHPGDALDH1A1KDM4ECYP1A2
	SCHEMBL2716340	0.82	EPHX2 (0.47)	KDM1AHDAC1ROS1SCN9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.