SCHEMBL27185166

SCHEMBL27185166

Cc1nc(C(=O)O)c(N)n1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.49
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
ALDH1A1 P00352 3/20 0.45
HTT P42858 2/20 0.45
CNR2 P34972 6/20 0.45
CNR1 P21554 4/20 0.45
MAPK1 P28482 3/20 0.45
PI4KA P42356 1/20 0.44
PI4K2B Q8TCG2 1/20 0.44
PI4K2A Q9BTU6 1/20 0.44
PI4KB Q9UBF8 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TSHR P16473 1/20 0.43
NOTUM Q6P988 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684239 0.83 CNR1 (0.57) HSD17B10ALDH1A1HTTCNR2CNR1
SCHEMBL1078089 0.81 CNR1 (0.56) HSD17B10ALDH1A1HTTCNR2CNR1
SCHEMBL5175569 0.77 PI4KA (0.54) HSD17B10ALDH1A1HTTMAPK1PI4KA
SCHEMBL16063426 0.77 CNR1 (0.54) HSD17B10ALDH1A1HTTCNR2CNR1
Adamantane SCHEMBL27759633 0.75 CNR2 (0.70) HSD17B10ALDH1A1HTTCNR2CNR1
SCHEMBL23889217 0.75 CNR1 (0.56) HSD17B10ALDH1A1HTTCNR2CNR1
SCHEMBL5376005 0.74 ALDH1A1 (0.49) HSD17B10ALDH1A1HTTMAPK1PI4KA
SCHEMBL27760017 0.73 CNR2 (0.64) HSD17B10ALDH1A1HTTCNR2CNR1
Lithium Ion SCHEMBL1078086 0.72 CNR2 (0.56) HSD17B10HTTCNR2CNR1MAPK1
SCHEMBL5782959 0.71 MDM2 (0.54) HSD17B10ALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240109848-A1 PROCESS FOR THE PREPARATION OF IMIDAZOBENZODIAZEPINES ODH IP Corp. (US) 2024-04-04 US disclosed
WO-2024059669-A2 IMPROVED PROCESS FOR THE PREPARATION OF IMIDAZOBENZODIAZEPINES ODH IP Corp. (US) 2024-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109848-A1 PROCESS FOR THE PREPARATION OF IMIDAZOBENZODIAZEPINES CYP3A4, CYP3A5, CYP3A7 HSD17B10 1498/4885PTGS1 2417/4885PTGS2 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.