SCHEMBL271855

SCHEMBL271855

CC(C)(C)OC(=O)N[C@H](CO)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.71
CYP3A4 P08684 5/20 0.58
MAPK1 P28482 1/20 0.58
APP P05067 4/20 0.58
CTSS P25774 3/20 0.57
CTSK P43235 2/20 0.57
CTSL P07711 1/20 0.57
CTSB P07858 1/20 0.57
ACE P12821 1/20 0.55
SYK P43405 1/20 0.53
KLK5 Q9Y337 1/20 0.51
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
AKT1 P31749 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1529562 1.00 ATM (0.71) ATMCYP3A4MAPK1APPCTSS
SCHEMBL257912 1.00 ATM (0.71) ATMCYP3A4MAPK1APPCTSS
SCHEMBL7857967 0.95 ATM (0.65) ATMCYP3A4MAPK1APPCTSS
SCHEMBL15521493 0.92 CTSS (0.62) ATMCYP3A4MAPK1APPCTSS
SCHEMBL1531592 0.92 CTSS (0.62) ATMCYP3A4MAPK1APPCTSS
SCHEMBL1531589 0.92 CTSS (0.62) ATMCYP3A4MAPK1APPCTSS
SCHEMBL15159951 0.90 ATM (0.73) ATMCYP3A4APPCTSSCTSK
SCHEMBL2291516 0.90 ATM (0.59) ATMCYP3A4MAPK1APPCTSS
SCHEMBL13669577 0.90 CTSS (0.67) ATMCYP3A4MAPK1APPCTSS
SCHEMBL20249542 0.89 ATM (0.59) ATMCYP3A4MAPK1APPCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025019172-A1 ANTIMICROBIAL EXTRACTANT FORMED FROM COPPER-CONTAINING SOURCE CORNING INCORPORATED (US) 2025-01-23 WO claimed
CN-117623988-A Synthesis method of N-Boc-L-phenylalaninol 常州锐博生物科技有限公司 2024-03-01 CN claimed
CN-116730873-A Synthesis method of N-Boc-L-phenylalaninol 常州锐博生物科技有限公司 2023-09-12 CN claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US claimed
EP-0820438-B1 O-CARBAMOYL-PHENYLALANINOL HAVING SUBSTITUENT AT BENZENE RING, ITS PHARMACEUTICALLY USEFUL SALTS AND METHOD FOR PREPARING THE SAME SK CORP (KR) 2001-06-20 EP claimed
EP-0820438-A1 O-CARBAMOYL-PHENYLALANINOL HAVING SUBSTITUENT AT BENZENE RING, ITS PHARMACEUTICALLY USEFUL SALTS AND METHOD FOR PREPARING THE SAME YUKONG LIMITED (KR) 1998-01-28 EP claimed
WO-1996032375-A1 O-CARBAMOYL-PHENYLALANINOL HAVING SUBSTITUENT AT BENZENE RING, ITS PHARMACEUTICALLY USEFUL SALTS AND METHOD FOR PREPARING THE SAME YUKONG LIMITED (KR) 1996-10-17 WO claimed
US-4978744-A Synthesis of dolastatin 10 ARIZONA BOARD OF REGENTS (US) 1990-12-18 US claimed
US-12583866-B2 Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists BEONE MEDICINES I GMBH (CH) 2026-03-24 US disclosed
US-20250353853-A1 FLAVIVIRUS INHIBITORS IRBM S.P.A. (IT) 2025-11-20 US disclosed
EP-4638446-A1 THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF Ventus Therapeutics U.S., Inc. (US) 2025-10-29 EP disclosed
EP-4532476-A1 FLAVIVIRUS INHIBITORS IRBM S.P.A. (IT) 2025-04-09 EP disclosed
US-20250110407-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD, AND RESIST BASE FILM FORMING COMPOSITION JSR CORPORATION (JP) 2025-04-03 US disclosed
EP-4069366-B1 ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF CHDI FOUNDATION INC (US) 2025-03-19 EP disclosed
US-4820712-A Sparsomycin (SC-RS) compounds having antitumor activity, a process for their preparation and pharmaceutical compositions containing sparsomycin (SC-RS) compounds STICHTING KATHOLIEKE UNIVERSITEIT (NL) 1989-04-11 US disclosed
WO-1988007053-A1 RENIN INHIBITORS CONTAINING A CYCLOPROPYL AMINO ACID AND/OR A CYCLOALKYL TRANSITION-STATE ANALOGUE THE UPJOHN COMPANY (US) 1988-09-22 WO disclosed
EP-0231919-A2 N-Heterocyclic alcohol renin inhibitors E.R. Squibb & Sons, Inc. (US) 1987-08-12 EP disclosed
EP-0218688-A1 DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS. UPJOHN CO (US) 1987-04-22 EP disclosed
US-4631270-A THIOMETHYLENE REPLACEMENTS RESEARCH CORPORATION (US) 1986-12-23 US disclosed
WO-1986006379-A1 DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS THE UPJOHN COMPANY (US) 1986-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583866-B2 Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists BIRC2, BIRC3, BIRC5 ATM 2668/4885CYP3A4 4330/4885MAPK1 2218/4885
US-20250353853-A1 FLAVIVIRUS INHIBITORS SPINT2, EIF2AK2, DDX5 ATM 4645/4885CYP3A4 1757/4885MAPK1 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.