Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733022 | 0.90 | TRPV1 (0.45) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2716871 | 0.90 | NPSR1 (0.47) | RBP4HSD17B10NPSR1TRPV1TRPA1 | |
| SCHEMBL4562323 | 0.88 | MEN1 (0.43) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2383852 | 0.86 | RBP4 (0.53) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2382710 | 0.86 | TRPV1 (0.51) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2385822 | 0.86 | TRPV1 (0.46) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2384857 | 0.86 | MEN1 (0.43) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2719957 | 0.85 | PANK3 (0.43) | RBP4ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2717889 | 0.85 | TRPV1 (0.45) | HSD17B10NPSR1TRPV1TRPA1KCNH2 | |
| SCHEMBL2717862 | 0.85 | NPSR1 (0.46) | RBP4HSD17B10NPSR1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | claimed |