Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | RBP4 | P02753 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718886 | 0.93 | CNR2 (0.40) | TRPV1RBP4NPSR1HSD17B10CA12 | |
| SCHEMBL2716168 | 0.90 | TRPV1 (0.42) | TRPV1RBP4NPSR1HSD17B10CA12 | |
| SCHEMBL2716556 | 0.90 | MEN1 (0.41) | TRPV1RBP4HSD17B10MEN1KMT2A | |
| SCHEMBL2716097 | 0.87 | MEN1 (0.39) | RBP4NPSR1HSD17B10MEN1KMT2A | |
| SCHEMBL2716167 | 0.87 | GAA (0.41) | TRPV1RBP4NPSR1HSD17B10CA12 | |
| SCHEMBL2716592 | 0.84 | TRPV1 (0.48) | TRPV1RBP4NPSR1HSD17B10CA12 | |
| SCHEMBL2718774 | 0.84 | CNR2 (0.43) | TRPV1RBP4GAAMEN1KMT2A | |
| SCHEMBL2715957 | 0.84 | MEN1 (0.42) | TRPV1RBP4HSD17B10MEN1KMT2A | |
| SCHEMBL2719291 | 0.83 | CNR2 (0.41) | TRPV1RBP4NPSR1HSD17B10GAA | |
| SCHEMBL2715967 | 0.83 | NPSR1 (0.41) | TRPV1RBP4NPSR1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | claimed |
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |