Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318015 | 0.98 | LMNA (0.56) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL15485653 | 0.96 | LMNA (0.54) | LMNAF2PRSS1CTSGCTRB1 | |
| Water SCHEMBL21440321 | 0.96 | LMNA (0.54) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL3311087 | 0.92 | NR4A2 (0.55) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL27634094 | 0.90 | NR4A2 (0.53) | LMNAF2PRSS1CTSGCTRB1 | |
| Water SCHEMBL28970354 | 0.90 | NR4A2 (0.53) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL28158437 | 0.90 | NR4A2 (0.53) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL7758809 | 0.89 | TDP1 (0.53) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL29172840 | 0.89 | TDP1 (0.53) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL1419304 | 0.88 | TSHR (0.48) | LMNAF2PRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240117106-A1 | POLYESTER COMPOSITIONS COMPRISING TETRAMETHYL CYCLOBUTANEDIOL AND 1,4-CYCLOHEXANEDIMETHANOL HAVING AN IMPROVED CATALYST SYSTEM COMPRISING TITANIUM AND ZINC | EASTMAN CHEMICAL COMPANY (US) | 2024-04-11 | — | — | US | claimed |