Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28970354 | 0.98 | NR4A2 (0.53) | NR4A2LMNAALDH1A1GAACYP2C19 | |
| SCHEMBL28158437 | 0.98 | NR4A2 (0.53) | NR4A2LMNAALDH1A1GAACYP2C19 | |
| SCHEMBL27634094 | 0.98 | NR4A2 (0.53) | NR4A2LMNAALDH1A1GAACYP2C19 | |
| SCHEMBL9318015 | 0.94 | LMNA (0.56) | NR4A2LMNAALDH1A1F2PRSS1 | |
| SCHEMBL27913952 | 0.92 | POLB (0.44) | NR4A2LMNAALDH1A1GAACYP2C19 | |
| Water SCHEMBL21440321 | 0.92 | LMNA (0.54) | NR4A2LMNAALDH1A1F2PRSS1 | |
| SCHEMBL15485653 | 0.92 | LMNA (0.54) | NR4A2LMNAALDH1A1F2PRSS1 | |
| SCHEMBL27192192 | 0.92 | LMNA (0.54) | NR4A2LMNAALDH1A1F2PRSS1 | |
| SCHEMBL7202703 | 0.89 | HDAC3 (0.56) | NR4A2LMNAALDH1A1GAACYP2C19 | |
| SCHEMBL11469404 | 0.89 | HDAC3 (0.52) | NR4A2LMNAALDH1A1GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104430311-A | Active bactericidal medicine as well as preparation method and special equipment thereof | BEIJING HYGIENE AND HEALTHCARE INOVATION TECHNOLOGY CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-8269023-B2 | Process for preparation of duloxetine hydrochloride | LUPIN LTD. (IN) | 2012-09-18 | — | — | US | claimed |
| US-20100105925-A1 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | LUPIN LIMITED (IN) | 2010-04-29 | — | — | US | claimed |
| EP-2132192-A2 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | Lupin Limited (IN) | 2009-12-16 | — | — | EP | claimed |
| WO-2008107911-A2 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | LUPIN LIMITED (IN) | 2008-09-12 | — | — | WO | claimed |
| CN-112742427-B | Startup method of hydrogenation catalyst | 中国石油化工股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-112742428-B | Preparation method of vulcanized hydrogenation catalyst | 中国石油化工股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113784755-A | Salts of isochroman-based compounds, crystalline forms thereof, processes for their preparation, their use in therapy and pharmaceutical compositions containing them | 赛诺维信制药公司 | 2021-12-10 | — | — | CN | disclosed |
| EP-2828369-B1 | LIQUID CLEANING AND DISINFECTING COMPOSITIONS | PROCTER & GAMBLE (US) | 2019-01-02 | — | — | EP | disclosed |
| EP-1695708-B1 | Highly concentrated minoxidil composition | STIEFEL RES AUSTRALIA PTY LTD (AU) | 2018-02-28 | — | — | EP | disclosed |
| EP-2827709-B1 | LIQUID CLEANING AND DISINFECTING COMPOSITIONS | PROCTER & GAMBLE (US) | 2017-09-06 | — | — | EP | disclosed |
| CN-104430311-B | Active bactericidal medicine as well as preparation method and special equipment thereof | 北京海洁海斯健康科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20100143842-A1 | METHOD FOR PRODUCING A COPOLYMER SOLUTION WITH A UNIFORM CONCENTRATION FOR SEMICONDUCTOR LITHOGRAPHY | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100105925-A1 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | LUPIN LIMITED (IN) | 2010-04-29 | — | — | US | disclosed |
| EP-2132192-A2 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | Lupin Limited (IN) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008107911-A2 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | LUPIN LIMITED (IN) | 2008-09-12 | — | — | WO | disclosed |
| US-6498275-B1 | Use of compounds for the elevation of pyruvate dehydrogenase activity | ASTRAZENECA AB (SE) | 2002-12-24 | — | — | US | disclosed |
| US-5405656-A | Electroless plating; then radiation | NIPPONDENSO CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0559216-A1 | Process for producing urethan foam having high-density skin layer | TOSOH CORPORATION (JP) | 1993-09-08 | — | — | EP | disclosed |
| EP-0281036-A2 | A process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105925-A1 | NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE | MAOA, SLC6A3, PNMT | NR4A2 1235/4885LMNA 1205/4885ALDH1A1 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.