Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721446 | 0.98 | MTNR1A (0.43) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL2720466 | 0.95 | KDM4E (0.40) | MTNR1AMTNR1B | |
| SCHEMBL10072544 | 0.94 | POLB (0.45) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL2718289 | 0.94 | POLB (0.44) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL2720447 | 0.93 | KDM4E (0.41) | MTNR1AMTNR1B | |
| SCHEMBL17213612 | 0.93 | MTNR1A (0.45) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL2720965 | 0.93 | POLB (0.48) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL2719424 | 0.92 | POLB (0.47) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL2716632 | 0.90 | POLB (0.50) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL15689940 | 0.90 | POLB (0.46) | POLBAPEX1HTTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012003136-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| EP-2401998-A1 | Dental composition, kit of parts and use thereof | 3M Innovative Properties Company (US) | 2012-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | MTNR1A 2334/4885MTNR1B 2337/4885POLB 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.