SCHEMBL17213612

SCHEMBL17213612

C=C(C)C(=O)OCCNC(=O)OC(COC(=O)C(=C)C)COc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MTNR1A P48039 2/20 0.45
▸ MTNR1B P49286 2/20 0.45
▸ POLB P06746 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2719066 0.96 MTNR1A (0.41) MTNR1AMTNR1B
SCHEMBL13017961 0.96 MTNR1A (0.43) MTNR1AMTNR1BPOLBAPEX1HTT
SCHEMBL2721760 0.93 MTNR1A (0.43) MTNR1AMTNR1B
SCHEMBL2719349 0.93 MTNR1A (0.42) MTNR1AMTNR1BPOLBAPEX1HTT
SCHEMBL17213611 0.92 MTNR1A (0.44) MTNR1AMTNR1BPOLBAPEX1HTT
SCHEMBL2720408 0.92 MTNR1A (0.43) MTNR1AMTNR1B
SCHEMBL18503933 0.92 THRB (0.47) MTNR1AMTNR1BL3MBTL1
SCHEMBL13002724 0.91 L3MBTL1 (0.44) MTNR1AMTNR1BPOLBAPEX1HTT
SCHEMBL13017923 0.91 MTNR1A (0.41) MTNR1AMTNR1BPOLBAPEX1HTT
SCHEMBL13017917 0.91 MTNR1A (0.41) MTNR1AMTNR1BPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3134446-B1 AROMATIC GLYCOL ETHERS AS CO-MONOMERS IN HOLOGRAPHIC PHOTOPOLYMER FORMULAS COVESTRO DEUTSCHLAND AG (DE) 2019-04-24 — — EP disclosed
US-9921473-B2 Aromatic glycol ethers as writing monomers in holographic photopolymer formulations COVESTRO DEUTSCHLAND AG (DE) 2018-03-20 — — US disclosed
US-9921473-B2 Aromatic glycol ethers as writing monomers in holographic photopolymer formulations COVESTRO DEUTSCHLAND AG (DE) 2018-03-20 — — US disclosed
US-20170045816-A1 AROMATIC GLYCOL ETHERS AS WRITING MONOMERS IN HOLOGRAPHIC PHOTOPOLYMER FORMULATIONS COVESTRO DEUTSCHLAND AG (DE) 2017-02-16 — — US disclosed
US-20170045816-A1 AROMATIC GLYCOL ETHERS AS WRITING MONOMERS IN HOLOGRAPHIC PHOTOPOLYMER FORMULATIONS COVESTRO DEUTSCHLAND AG (DE) 2017-02-16 — — US disclosed
WO-2015161969-A1 AROMATIC GLYCOL ETHERS AS WRITING MONOMERS IN HOLOGRAPHIC PHOTOPOLYMER FORMULATIONS BAYER MATERIAL SCIENCE AG (DE) 2015-10-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170045816-A1 AROMATIC GLYCOL ETHERS AS WRITING MONOMERS IN HOLOGRAPHIC PHOTOPOLYMER FORMULATIONS MARK3, KDM3A, MAP1LC3B MTNR1A 3707/4885MTNR1B 3907/4885POLB 3654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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